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Pharmaceutical Grade Bulk Food Additive Trehalose Powder

Pharmaceutical Grade Bulk Food Additive Trehalose Powder

Brand Name : Allforlong
Model Number : Food grade
Certification : ISO9001, ISO14001
Place of Origin : Qingdao China
MOQ : 1ton
Price : negotiate
Payment Terms : L/C, T/T
Supply Ability : 2000tons
Delivery Time : 20days
Packaging Details : carton5.0kg, 10.0kg, 20kg or as per demands
Molecular formula : C12H22O11•2H2O
English Name : D-(+)-Trehalose dehydrate
CAS NO. : 6138-23-4
Appearance : white powder crystal
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Pharmaceutical Grade Bulk Food Additive Trehalose Powder CAS NO. 6138-23-4


1. Quick Detail :


◆Trehalose is a kind of safe, reliable natural carbohydrate which widely exists in many edible plants and animals and microorganisms of the nature , there are usually too much content trehalose in many plants and aminals body , such as mushrooms, seaweed, beans , shrimp, bread, beer and yeast food.


◆Trehalose has magic protective with organisms, under high temperature, heavy cool, high osmotic pressure and drying etc. other harsh environmental conditions, trehalose can form a unique protective film on the cell surface,and effectively protect the protein molecular invariance not to inactivate,and keep life process and biological characteristics, so, trehalose is also known as "the life of sugar"


2. Description :


Mild sweetness:Trehalose is only 45% as sweet as sucrose. It has a clean taste profile

Process stability:Trehalose is a non-reducing sugar and will not take part in Mallard reactions with amino acids or proteins during the manufacturing processing and storage even at elevated temperatures.Thus, trehalose can be favorably used in food and beverage where heat treatment is required or storage at high temperature.


◆ Perfect heat and acid tolerance: Trehalose is very stable to heat and acid during processing and storage, and would not become colored and broken down even heated for 30min at 100℃, pH3.0.

◆ Low solubility and excellent crystalline:Water-solubility of trehalose is as high as maltose while the crystallinity is excellent, so it is easy to produce the low hygroscopical candy, coating, soft confectionery etc.


◆ Low hygroscopicity:Some foods themselves are not hygroscopic, but their hygroscopicity can rapidly increase once sugars such as sucrose and maltose is added, and then foods’ original flavor and shelf life changed. Trehalose has a very low hygriscopicity and remains stable up to 95% relative humidity. Thus, trehalose can be used as sweetening in food process.

◆ High Glass Transition Temperature:The glass transition temperature of trehalose is 120℃, which makes trehalose ideal as a protein protectant and ideally suited as a carrier for spray-dried flavors.


3. Applications :

In Medical Industry Trehalose is widly used in these following fields
◆.. Trehalose has been successfully applied to blood products such as vaccine, lymphocyte and other cytokines to stabilize their activities. Trehalose can not only be conserved at an ambient temperature, but also prevent some vital disease such as hepatitis B and AIDS caused by contaminated blood resource from transforming.
◆..Quadrant Research Fund Association, England, found that vaccines and other temperature-vulnerable biologicals which usually require cold storage at 4 ℃ is stable at 45℃ after mixture with trehalose. Thus, the cost of storage and transportation will be greatly decreased while maintaining high potential of vaccine undergoing a far distance transportation.
◆..In California, America, John Calau and his collegues has successfully applied trehalose to preserve blood platelet by dehydrating cells and hyophilization, and the platelet can be preserved for a long time at an ambient temperature and showed survival percentage of 85%.
◆.. Trehalose can be used to keep biological agents such as enzyme, cell membrane, organelle, antibody and virus, and make life-science research more convenient, rapid and effective. Research on the protective function of trehalose on restriction enzyme, DNA ligase and DNA polymerase has been carried out, and results showed that all enzyme samples with addition of trehalose, kept 35 days at 70℃ or 9 months at 37℃, maintained nearly 100% of their original activities. The Chinese scientists tested three diagnostic enzymes which were prepared with trehalose as disccant to assay human serum cholesterol, and found that trehalose could keep 90% of their activity after long-term storage at an ambient temperature.
◆.. Using trehalose as lyophilization protectant can efficiently retain activity of vaccine for domestic animals and poultry and virus-vaccine for man, for example, attenuated hepatitis A virus vaccine, epidemic encephalitis B vaccine. And the inoculated efficiency of vaccine can be kept without low temperature storage and freezing transportation.

4. Specifications :


Item

Specification

Formula

2H2O (dihydrate)

Description

White crystal with a sweet taste, virtually odorless

Assay

Not less than 98%

Loss on drying

Less than 2.0% (60℃, 5h)

Total ash

Less than 0.06%

Lead

Less than 1mg/kilo

Arsenic

Less than 1mg/kilo

Coliform

Less than 30 MPN/100g

pH

5.0 - 6.7

Total aerobic counts

Less than 400 CFU per gram

Salmonella

Negative

Package

5kg,10kg, 20kg


5. Competitive Advantage :

Allforlong strictly carries out ISO9001: 2000 and HACCP and passed the examination and verifying of the identification organization in 2008. The Producing Department is responsible to prevent and control the quality of product. We has established strictly Product Tracking System and practised the quality standardized control from the material to finished product. We also set up the Quality Test Department which is responsible for detecting the samples of every process, so that promptly find out the possible quality problem and then take precautions.



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